Higher-order dearomative 10+2 cycloaddition of 2-nitrobenzofurans and 2-alkylidene-1-indanones to access pentacyclic scaffolds

Key Points

• This research aims to explore higher-order dearomative cycloadditions for creating complex structures.
• Performed a higher-order dearomative [10+2] cycloaddition
• Used 2-nitrobenzofurans and 2-alkylidene-1-indanones
• Accessed pentacyclic scaffolds.
• Developed new structural motifs in polycyclic frameworks
• Showed efficiency and atom-economy in synthesis.