3D-printed GelMA/BC@PLLAms-Cur@TCP-PCL-PEG bilayer scaffold for osteochondral repair

Key Points

• This research focuses on developing a bilayer scaffold for effective osteochondral repair.
• Fabrication of a 3D-printed bilayer scaffold using GelMA and other materials.
• Assessment of scaffold properties, including mechanical support and drug release profiles.
• Evaluation of biological responses related to chondrogenesis and osteogenesis.
• The upper layer successfully promotes chondrogenesis with collagen.
• The lower layer supports mechanical integrity and provides sustained curcumin release.
• Curcumin release demonstrates anti-inflammatory and osteogenic effects.

Abstract