Methemoglobin and Nitrogen Dioxide Levels During Inhaled Nitric Oxide Therapy at 300 Parts per Million in Healthy Volunteers

Key Points

• The study aims to evaluate the safety of intermittent inhaled nitric oxide therapy in monitoring methemoglobin and nitrogen dioxide levels.
• Intermittent iNO300 administration was used.
• Real-time monitoring of MetHb and NO2 levels was performed.
• Healthy adults participated as subjects in the study.
• iNO300 therapy did not adversely affect methemoglobin levels.
• NO2 levels remained within safe limits during therapy.
• Findings support further research on iNO300 for respiratory infections.