ABSTRACT Constructing structurally well‐defined copper‐based polyoxovanadates (POVs) catalysts for azide–alkyne cycloaddition is an attractive yet challenging research objective. Herein, three copper‐based POVs hybrids, formulated, respectively, as Cu(dpa)V 2 O 6 ( 1 ), Cu(bipy)V 2 O 6 ( 2 ), Cu(phen)(H 2 O)V 2 O 6 ( 3 ) (dpa = 2,2′‐dipyridylamide, bipy = 2,2′‐bipyridine, phen = 1,10‐phenanthroline) were successfully synthesized and fully characterized. Importantly, the three hybrids showed high efficiency for the azide–alkyne cycloaddition under mild conditions, and the yields were up to 99% because they integrate the catalytic ability of Cu sites with the multielectron‐transfer ability of POVs. Moreover, the reusability of 3 was further investigated, and no significant decrease in catalytic activity was observed. These results indicate a sustainable molecular‐level strategy to expand the application of POVs in the azide–alkyne cycloaddition for constructing triazole derivatives.
Jiang et al. (Sat,) studied this question.