Lip and oral involvement in 116 patients with xeroderma pigmentosum in the UK

Key Points

• The study aims to characterize the oral involvement in patients with xeroderma pigmentosum and identify subgroups at increased risk of complications.
• Analyzed clinical characteristics of a cohort of 116 patients with xeroderma pigmentosum.
• Categorized patients into different XP subgroups according to their specific risks.
• Evaluated the incidence of malignant transformations in the lip and oral mucosa.
• Identified significant rates of malignant transformation in specific XP subgroups.
• Documented varied manifestations of oral mucosal involvement among patients.
• Provided data indicating the need for targeted monitoring in high-risk groups.