Sex‐ and age‐dependent differences in detrimental repolarization‐prolonging effects of doxorubicin: Evidence of cardiac toxicity beyond heart failure

Key Points

• To investigate how sex and age influence the cardiac toxic effects of doxorubicin beyond heart failure.
• Examined the effects of doxorubicin on cardiac repolarization.
• Analyzed data across different sexes and age groups.
• Assessed the implications for cardiac health beyond heart failure.
• Identified significant variations in repolarization effects based on sex.
• Observed notable age-dependent differences in drug response.
• Highlighted the risk of cardiac toxicity unrelated to heart failure symptoms.