What question did this study set out to answer?

This research focuses on understanding very late stent fractures, especially with first-generation drug-eluting stents.

March 17, 2026JACC Case Reports0 citationsOpen Access

Very Late Fracture of a First-Generation Drug-Eluting Stent

FTFlora Tsakirian DADimitrios Afendoulis STSotirios Tsalamandris

Key Points

This research focuses on understanding very late stent fractures, especially with first-generation drug-eluting stents.
Analysis of cases involving late stent fracture
Evaluation of patient symptoms and ischemic evidence
Assessment of angiographic appearances in relation to symptoms
Very late fractures can happen decades post-implantation
Management should prioritize symptoms over angiographic findings
Evidence shows variability in patient outcomes based on symptom-guided approaches

Abstract

Very late stent fracture may occur decades after implantation, particularly with the use of first-generation drug-eluting stents. Management should be guided by patient symptoms and evidence of ischemia rather than angiographic appearance alone.

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