Comparative Efficacy of Elinzanetant Versus Other Non‐Hormonal Pharmaceutical Therapies for the Treatment of Moderate‐to‐Severe Vasomotor Symptoms Associated With Menopause: A Network Meta‐Analysis

Key Points

• This analysis aims to compare the efficacy of elinzanetant with other non-hormonal therapies for managing vasomotor symptoms during menopause.
• Conducted a network meta-analysis to evaluate various non-hormonal therapies.
• Included indirect comparisons of elinzanetant with other treatments.
• Assessed frequency and severity of vasomotor symptoms and improvements in sleep disturbances.
• Elinzanetant demonstrated superior or comparable efficacy to non-hormonal therapies.
• Significant reduction in the frequency of vasomotor symptoms was observed.
• Improvement in sleep disturbances was noted with elinzanetant compared to alternatives.