Effect of italicJuantong Decoction/italic （蠲痛饮） combined with dienogest in the treatment of endometriosis and its effect on the inflammatory-oxidative stress state

Key Points

• The study examines the efficacy of Juantong Decoction combined with dienogest in treating endometriosis and its impact on inflammatory and oxidative stress markers.
• 200 endometriosis patients were randomized into four groups: combination therapy, Juantong Decoction only, dienogest only, and control group.
• Various outcomes were analyzed, including inflammatory markers, oxidative stress indicators, CA125 levels, pain scores, and cyst diameter.
• Assessments were made before and after treatment to evaluate effects.
• No significant differences in outcomes before treatment among groups (P>0.05).
• Post-treatment, significant improvements were seen in the combination group for MDA, GSH-Px, T-SOD, IL-6, CA125, cyst size, dysmenorrhea, and hormone levels (P<0.05).
• Combination therapy yielded the best results compared to other groups.