Biodegradable Folate-Mediated Chitosan-CQD Nanocarriers for Targeted and Stimuli-Responsive Cisplatin Delivery in Melanoma

Key Points

• The research aims to develop biodegradable chitosan-based nanocarriers for targeted delivery of cisplatin in melanoma treatment.
• Development of chitosan-cQD nanocarriers
• Evaluation of drug loading capacity
• Assessment of targeted release mechanism
• In vitro testing on melanoma cells
• Nanocarriers showed high drug-loading efficiency
• Enhanced targeted delivery of cisplatin observed
• Stimuli-responsive release mechanisms demonstrated effective cancer cell inhibition