To investigate how postnatal creatinine levels influence plasma gentamicin concentrations in neonates.
Analyzed postnatal creatinine levels and plasma gentamicin concentrations.
Utilized PMA for initial gentamicin dosing decisions.
Evaluated renal function parameters for guiding maintenance dosing.
PMA-based dosing is preferred for initial gentamicin on day 0.
Cr-based parameters are more effective for maintenance dosing.
Abstract
PMA-based dosing appears to be preferable for determining initial GM dosing on postnatal day 0, whereas Cr-based renal function parameters may be more effective for guiding maintenance dosing.