What question did this study set out to answer?

To investigate the histopathological features contributing to peritumoral enhancement in muscle-invasive bladder cancer.

March 21, 2026Magnetic Resonance in Medical Sciences0 citationsOpen Access

Histopathological Basis of Peritumoral Enhancement in Muscle-invasive Bladder Cancer

HWHiroyuki Watanabe MTMitsuru Takeuchi AHAtsushi Higaki

Key Points

To investigate the histopathological features contributing to peritumoral enhancement in muscle-invasive bladder cancer.
Conducted histopathological examination of tumor samples
Analyzed stromal characteristics at tumor invasive front
Measured microvessel density in surrounding tissue
Identified significant peritumoral fibrosis around invasive tumors
Increased microvessel density correlated with peritumoral enhancement

Abstract

PTE reflects localized stromal remodeling at the tumor invasive front, characterized predominantly by marked peritumoral fibrosis accompanied by increased microvessel density.

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