Osteoarthritis and cardiometabolic diseases: shared mechanisms, modifiable risk factors, and integrated management strategies

Key Points

• The research aims to explore the interconnected mechanisms between osteoarthritis and cardiometabolic diseases and identify modifiable risk factors.
• Investigate shared molecular pathways using multi-omics approaches.
• Validate early-detection biomarkers for osteoarthritis and cardiometabolic diseases.
• Assess multimodal interventions that connect musculoskeletal and metabolic health.
• Identified various shared molecular pathways between osteoarthritis and cardiometabolic diseases.
• Validated specific biomarkers that may aid in early detection.
• Demonstrated that a patient-centered approach can enhance management strategies.

Abstract