Impact of Basal Ganglia Perivascular Spaces on Ischemic and Hemorrhagic Risks in Patients Taking Antithrombotic Therapies

Key Points

• The research aims to evaluate the relationship between basal ganglia perivascular space burdens and ischemic and hemorrhagic risks in patients undergoing antithrombotic therapy.
• Observational assessment of basal ganglia perivascular spaces through imaging techniques.
• Comparison of ischemic stroke and major bleeding incidents in patients on antithrombotic therapy.
• Statistical analysis to correlate BGPVS burdens with ischemic and hemorrhagic outcomes.
• Higher burdens of basal ganglia perivascular spaces are significantly associated with increased risks of ischemic stroke.
• Increased BGPVS burdens are linked to a greater risk of major bleeding events.
• BGPVS may act as effective imaging biomarkers for assessing vascular risk.