A General and Scalable DNA Nano-chip with Fully Localized Architecture Enables Biocomputing in Living cells and Precisely Induces Cell Apoptosis

Key Points

• The aim is to develop a scalable DNA nano-chip that can perform biocomputing and induce apoptosis in cells.
• Developed a DNA nano-chip with fully localized architecture.
• Demonstrated DNA logic circuits mimicking silicon electronics.
• Examined the ability to control cellular functions through DNA components.
• The nano-chip successfully induced cell apoptosis in targeted cells.
• It showcased improved control over DNA logic components compared to previous methods.