A pH-sensitive nanoplatform encapsulating lipid droplets specific near-infrared fluorescent probe for in vivo imaging of mice carotid artery plaques

Key Points

• The aim is to develop a pH-sensitive nanoplatform to track lipid droplets for imaging atherosclerotic plaques.
• Developed a nanoplatform encapsulating lipid droplets
• Utilized a near-infrared fluorescent probe
• Conducted in vivo imaging in mouse models of atherosclerosis
• Achieved effective monitoring of lipid droplets in real-time
• Enhanced imaging contrast in atherosclerotic plaques
• Demonstrated potential for precise diagnosis and monitoring of arterial diseases