What question did this study set out to answer?

To explore the efficiency of chalcogen-bonding catalysis in facilitating carbonyl–olefin metathesis reactions involving cycloalkenes and aldehydes.

March 26, 2026

Chalcogen-Bonding Catalysis Approach to Intermolecular Ring-Opening Carbonyl–Olefin Metathesis

Key Points

To explore the efficiency of chalcogen-bonding catalysis in facilitating carbonyl–olefin metathesis reactions involving cycloalkenes and aldehydes.
Utilized chalcogen-bonding catalysis for carbonyl–olefin metathesis.
Conducted reactions using five- to seven-membered cycloalkenes and aldehydes.
Evaluated the product formation from these reactions.
Observed successful intermolecular ring-opening metathesis products from cycloalkenes and aldehydes.
Determined that cycloalkenes exhibited otherwise low reactivity under traditional acid catalysis.

Abstract

While carbonyl–olefin metathesis has emerged as an important type of reaction, cycloalkenes have shown no or low reactivity toward aldehydes under strong Lewis or Brønsted acid catalysis. Herein, we report that, enabled by chalcogen-bonding catalysis, reactions between five- to seven-membered cycloalkenes and aldehydes proceeded to afford intermolecular ring-opening metathesis products.

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Authors

Baojie Yu

Yao Wang

Journals

Organic Letters

Actions

Institutions

Shandong University

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Building similarity graph...

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Chalcogen-Bonding Catalysis Approach to Intermolecular Ring-Opening Carbonyl–Olefin Metathesis

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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