Mild and efficient synthesis of carbamates using dioxazolones as bench-stable isocyanate surrogates: application in AChE-inhibiting agent development

Key Points

• The aim is to create a practical approach for synthesizing carbamates using dioxazolones as isocyanate surrogates.
• Developed a synthesis method for carbamates
• Utilized 3-substituted dioxazolones as isocyanate substitutes
• Targeted acetylcholinesterase inhibition for application
• Successfully synthesized carbamates using the novel method
• Proved the efficiency of dioxazolones as isocyanate surrogates
• Indicated potential for developing AChE-inhibitors