The magnitude of the pharmacodynamic index for NOSO-502: pathogen clearance, emergence of resistance and human dose predictions

Key Points

• The research aims to estimate effective doses of NOSO-502 in humans while analyzing its impact on pathogen clearance and resistance emergence.
• Utilized pharmacodynamic index (PDI) targets.
• Estimated human pharmacokinetics of NOSO-502.
• Analyzed dose-effect relationships.
• Effectively estimated doses of NOSO-502 for human use.
• Showed potential for significant pathogen clearance.
• Identified implications for resistance emergence.