Understanding Candidozyma (Candida) auris: genomic evolution, antifungal resistance and the growing challenges in global infection control

Key Points

• This research aims to explore the genomic evolution of Candidozyma auris and its implications for antifungal resistance and global infection control.
• Analyzed genetic clades of Candidozyma auris
• Evaluated antifungal resistance mechanisms
• Assessed biofilm formation and persistence in hospital environments
• Candidozyma auris exhibits six distinct genetic clades
• High rates of antifungal resistance contribute to elevated mortality
• The fungus shows strong adaptability to environmental stressors