Estimating the sensitivity of non-treponemal and treponemal antibody tests in primary syphilis

Key Points

• Evaluate the sensitivity of non-treponemal and treponemal antibody tests during primary syphilis diagnosis.
• Compared sensitivity of TRUST and RPR tests against darkfield microscopy and PCR.
• Calculated sensitivity percentages using samples from patients diagnosed with primary syphilis.
• Analyzed data from multiple antibody tests including TPPA.
• TRUST sensitivity was 55% compared to darkfield microscopy.
• RPR sensitivity was 78% and 93% compared to DFM and PCR respectively.
• TPPA showed high sensitivity of 95% against DFM and 96% against PCR.