A close and bidirectional relationship exists between telomere biology and T2DM. Deeper insights into this association not only enhance our understanding of T2DM pathogenesis but also offer potential therapeutic targets for anti-aging-based interventions, highlighting important clinical translation prospects. Future research should further clarify the causal relationships involved and explore strategies aimed at preserving telomeres or modulating telomerase activity to delay diabetes progression and prevent its complications, thereby advancing novel approaches for early risk assessment and precision management of T2DM.
Cao et al. (Sun,) studied this question.