High-dose intravenous methylprednisolone is effective in subacute thyroiditis unresponsive to oral steroids.

Key Points

• This research aims to evaluate the effectiveness of high-dose intravenous methylprednisolone in treating subacute thyroiditis not responding to oral steroids.
• Administered high-dose intravenous methylprednisolone to patients with subacute thyroiditis.
• Monitored clinical and ultrasonographic changes after treatment.
• Assessed safety, tolerability, and incidence of hypothyroidism during follow-up.
• Most patients showed rapid clinical improvement after IVMP therapy.
• Ultrasonographic findings improved significantly in treated patients.
• The treatment allowed for a shorter duration with good tolerability and few adverse events.