Prenatal 17‐Alpha‐Hydroxyprogesterone Caproate Exposure in Twins and Childhood Outcomes: 14‐Year Follow‐Up of a Randomised Trial

Key Points

• This research aims to evaluate the impact of prenatal 17-OHPC exposure on childhood outcomes in twins.
• Conducted a randomized trial with women pregnant with twins.
• Administered 17-OHPC during pregnancy.
• Followed up on children's mortality, educational attainment, cognition, and behavior over 14 years.
• No significant positive or negative effects of 17-OHPC on child mortality.
• No impact on educational attainment in offspring.
• Cognitive and behavioral outcomes remained unaffected.