Proteinuria remission is the most significant prognostic factor in childhood IgA nephropathy (c-IgAN). However, the time required to achieve proteinuria remission after treatment initiation varies among patients, depending on clinical presentation, histopathological findings, and treatment modalities. Clinicians often face uncertainty in determining whether to continue current therapy or modify the treatment plan based on the course of proteinuria. Clarifying the optimal timing for proteinuria remission may aid in clinical decision-making.
Shima et al. (Wed,) studied this question.