Size-based sorting of cancer cells reveals functional heterogeneity among subpopulations

Key Points

• This study aims to investigate the functional significance of size and morphological heterogeneity in cancer cells.
• Size-based sorting of cancer cells
• Analysis of functional traits among sorted subpopulations
• Assessment of morphology and pleomorphism
• Significant differences in functionality observed among various sorted subpopulations.
• Larger cancer cells displayed distinct morphological characteristics compared to smaller counterparts.
• Heterogeneity correlates with poorer prognosis based on established pathology indicators.