Conclusion: NEDD4L should be added to genetic panels for hypertension, NDI and SNHL, and NEDD4L-LiNDID should be suspected in patients with unexplained LS, NDI or SNHL.LiNDID patients will rapidly benefit from treatment with amiloride, an effective, cheap, and widely available life-saving drug.Note: An earlier version of this work, presenting only one affected patient and less functional work, was presented at ASN meeting in 2023.I have no potential conflict of interest to disclose.I did not use generative AI and AI-assisted technologies in the writing process.
Yagi et al. (Wed,) studied this question.