Adverse drug reactions among children with tuberculosis in China: a multicentre study, 2017–2022

Key Points

• This study aims to identify the prevalence and types of adverse drug reactions in children with tuberculosis in China.
• Conducted a multicentre observational study across various hospitals
• Focused on paediatric TB patients receiving treatment from 2017 to 2022
• Analyzed the types and severity of adverse drug reactions
• Adverse drug reactions were common among patients, especially haematological and gastrointestinal types
• These reactions were mostly transient during the intensive treatment phase
• Patients with severe disease or on specific drug regimens faced higher risks of ADRs