What question did this study set out to answer?

This report aims to explore the effectiveness of combined therapy in treating endobronchial oligometastatic breast cancer.

March 28, 2026Surgical Case Reports0 citationsOpen Access

Pathological Complete Response after Robot-Assisted Pulmonary Resection Following CDK4/6 Inhibitor–Combined Endocrine Therapy for Endobronchial Oligometastatic Breast Cancer: A Case Report

HNHikari Nitahara WGWataru Goto MNMariko Nishikawa

Key Points

This report aims to explore the effectiveness of combined therapy in treating endobronchial oligometastatic breast cancer.
Case report detailing a patient with endobronchial metastasis from breast cancer
Treatment involved endocrine therapy combined with a CDK4/6 inhibitor
Followed by robotic-assisted pulmonary resection for local control.
Patient achieved pathological complete response after the combination therapy
Surgical resection was performed successfully with no residual tumor detected.

Abstract

INTRODUCTION: Endobronchial metastasis from breast cancer is rare. Even in oligometastatic disease, systemic therapy remains the standard treatment, and the role of surgical resection is not well established. We report a case of endobronchial oligometastatic breast cancer that achieved pathological complete response (pCR) after endocrine therapy combined with a cyclin-dependent kinase 4/6 (CDK4/6) inhibitor, followed by pulmonary resection.

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Nitahara et al. (Thu,) studied this question.

synapsesocial.com/papers/69c770c08bbfbc51511e0c21 https://doi.org/https://doi.org/10.70352/scrj.cr.26-0010

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