WCN26-6657 KLOTHO DEFICIENCY AND IMPAIRED POTASSIUM HOMEOSTASIS: INVOLVEMENT OF mTORC1 SIGNALING

Key Points

• The aim is to understand how Klotho deficiency affects potassium homeostasis through mTORC1 signaling.
• Examined the role of Klotho in potassium balance.
• Analyzed the involvement of mTORC1 signaling pathways.
• Monitored serum sodium levels as a potential marker for disturbance.
• Klotho deficiency leads to impaired potassium homeostasis.
• Alteration in mTORC1 signaling pathways associated with Klotho deficiency.
• Serum sodium levels may serve as indicators of potassium imbalance.