High night-to-night variability in OSA severity is associated with prevalent cardiovascular disease

Key Points

• The study aims to explore the relationship between night-to-night variability in OSA severity and cardiovascular disease.
• Analyzed variability in OSA severity across multiple nights.
• Examined associations with prevalence of non-fatal MACCEs.
• Proposed prospective trials to understand causal mechanisms.
• High night-to-night variability in OSA is linked to higher odds of experiencing non-fatal MACCEs.
• Identified a potential connection between OSA severity fluctuations and cardiovascular health.