This study aims to develop a bedside treatment algorithm to ensure the safe administration of high-dose methotrexate in adults with acute lymphoblastic leukemia.
Creation of a treatment algorithm based on existing protocols.
Consideration of patient-specific factors for drug administration.
Evaluation of safety and efficacy during administration.
The algorithm enhances safety in drug administration.
Improved adherence to treatment protocols was observed.
Reduction in the incidence of adverse effects related to high-dose methotrexate.