Development of a Panel of Molecular Biomarkers of Asthma: Analysis of Differential Expression and Stability Over Time | Synapse
March 28, 2026Open Access
Development of a Panel of Molecular Biomarkers of Asthma: Analysis of Differential Expression and Stability Over Time
Key Points
The research aims to identify a set of molecular biomarkers for diagnosing and classifying asthma based on gene expression.
Developed a diagnostic algorithm using gene expression profiles.
Analyzed expression of 8 specific genes in peripheral blood mononuclear cells (PBMCs).
Assessed differential expression and stability of biomarkers over time.
Identified 8 genes that show significant differences in expression between asthma phenotypes.
Demonstrated the potential of these biomarkers to guide clinicians in asthma diagnosis.
Proposed a robust method for monitoring changes in gene expression over time.
Abstract
We propose a diagnostic algorithm based on the expression profiles of 8 genes in PBMCs that could guide clinicians in the diagnosis and phenotypic classification of asthma.
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Cite This Study
Cremades-Jimeno et al. (Thu,) studied this question.