Heck-type C-glycosylations in the synthesis of artificial nucleotides and functional nucleic acids

Key Points

• The aim is to address the challenges in synthesizing nucleosides through effective glycosylation methods.
• Utilized Heck-type reactions for C-glycosylation
• Synthetized various artificial nucleobases
• Analyzed the effectiveness of the glycosylation processes
• Successfully produced multiple artificial nucleotides
• Enhanced efficiency in synthesizing glycosidic bonds
• Demonstrated potential for new functional nucleic acids