What question did this study set out to answer?

This research aims to assess the antimicrobial resistance patterns of Streptococcus agalactiae in dairy-producing provinces of northern China.

March 29, 2026

Research communication: Regional variation in antimicrobial resistance of Streptococcus agalactiae isolated from bovine mastitis in major dairy-producing provinces of northern China

Key Points

This research aims to assess the antimicrobial resistance patterns of Streptococcus agalactiae in dairy-producing provinces of northern China.
Evaluated 128 isolates of Streptococcus agalactiae from Shandong, Hebei, and Inner Mongolia.
Used the broth microdilution method to assess antibiotic resistance.
Analyzed regional variations in antimicrobial resistance and minimum inhibitory concentrations.
Isolates showed 100% resistance to penicillin, ceftiofur, amoxicillin, cefquinome, and vancomycin.
Significant resistance to tetracycline (80.7%) and daptomycin (99.3%).
Inner Mongolia isolates had higher resistance and MIC values, indicating regional differences in antibiotic usage.

Abstract

Streptococcus agalactiae, a major bovine mastitis pathogen, poses significant economic and antimicrobial resistance (AMR) challenges. This study evaluated AMR in 128 isolates from Shandong, Hebei and Inner Mongolia using the broth microdilution method. Results showed high sensitivity to most antibiotics (e.g. 100% resistance to penicillin, ceftiofur, amoxicillin, cefquinome and vancomycin) but significant resistance to tetracycline (80.7%) and daptomycin (99.3%). Inner Mongolia isolates exhibited higher resistance and mimimum inhibitory concentrations (MIC) values, reflecting regional antibiotic usage differences, guiding mastitis treatment and antibiotic stewardship in China's dairy industry.

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Research communication: Regional variation in antimicrobial resistance of Streptococcus agalactiae isolated from bovine mastitis in major dairy-producing provinces of northern China

Key Points

Abstract

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