Construction of a Controllable Self-Assembled Dual-Mode Al 3+ Sensor Based on Substituent Effects of Flavonoids

Key Points

• The study aims to explore how substituents in flavonoids affect their self-assembly and sensing capabilities for Al3+.
• Examined the role of hydroxyl substituents in flavonoid tautomerism.
• Investigated the self-assembly processes driven by hydrophilicity-hydrophobicity and π-π interactions.
• Developed a dual-mode sensor for Al3+ based on these properties.
• Demonstrated that hydroxyl groups significantly influence proton transfer in flavonoids.
• Showed that substituent characteristics affect the efficiency of self-assembly for sensing.
• Established a functional sensor capable of detecting Al3+ ions.