What type of study is this?

This is a Human Clinical Trial study.

What question did this study set out to answer?

To evaluate the effect of CL16019 on the healing rate of distal radius fractures alongside standard therapy.

March 30, 2026Journal of Integrative and Complementary Medicine0 citations

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CL16019, A Combination of Cissus quadrangularis and Boswellia serrata Extracts Promotes the Healing of Distal Radius Fractures: A Multicentric, Randomized, Open-Label Study

AMAnjaneya Venkata Vara Prasad Mungara NSNawazish Rabbani Shaik CMChandra Kiran M

Key Points

To evaluate the effect of CL16019 on the healing rate of distal radius fractures alongside standard therapy.
Conducted as a multicentric, randomized, open-label study
Participants received either CL16019 with standard therapy or only standard therapy
Registered with the Clinical Trial Registry of India (CTRI)
CL16019 enhanced the bone fracture healing rate
Accelerated callus formation
Improved cortical bridging in patients receiving CL16019

Abstract

Supplementation of CL16019 along with standard therapy was found to enhance the bone fracture healing rate, possibly by accelerating the callus formation rate and enhancing cortical bridging. These findings imply that CL16019 might be a good adjunctive in addition to ST for the faster healing of DRFs. The trial was registered with the Clinical Trial Registry of India (CTRI) with the registration number CTRI/2021/12/039006, on December 29, 2021.

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CL16019, A Combination of Cissus quadrangularis and Boswellia serrata Extracts Promotes the Healing of Distal Radius Fractures: A Multicentric, Randomized, Open-Label Study

Key Points

Abstract

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