What question did this study set out to answer?

The study aims to explore how life experiences of humiliation and entrapment influence anxiety and depression symptoms in adolescents.

April 1, 2026Open Access

Life experiences of humiliation, entrapment, and frontoparietal-cerebellar connectivity predict adolescent anxiety and depression symptoms

YQYueyue QuYale University SCSidhant Chopra SQShijie QuYale University

Key Points

The study aims to explore how life experiences of humiliation and entrapment influence anxiety and depression symptoms in adolescents.
Analyzed lifetime exposures to humiliation and entrapment as stressors.
Investigated frontoparietal and cerebellar connectivity in adolescents.
Assessed internalizing symptoms using psychological evaluation tools.
Lifetime humiliation and entrapment correlate with increased anxiety and depression symptoms.
Frontoparietal-left cerebellar connectivity serves as a potential stress-sensitive marker for internalizing problems in adolescents.

Abstract

Our study highlights lifetime exposures to humiliation and entrapment as central stressor characteristics linked to adolescent internalizing symptoms. Our results also suggest that frontoparietal-left cerebellar connectivity may be a stress-sensitive marker of adolescent internalizing problems over time.

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