What question did this study set out to answer?

The study aims to assess the effectiveness of pre-hospital testing for neurological outcomes after out-of-hospital cardiac arrest.

April 1, 2026European Heart Journal Acute Cardiovascular Care0 citationsOpen Access

Point-of-care testing for pre-hospital stratification after out-of-hospital cardiac arrest: the RAPID-MIRACLE study

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MRMuhamad Abd Razak PJP. Jeyaprakash MMMichael McGarvey

Key Points

The study aims to assess the effectiveness of pre-hospital testing for neurological outcomes after out-of-hospital cardiac arrest.
Evaluated the pre-hospital application of ROSC-MIRACLE2 for neurological risk assessment.
Compared point-of-care pH testing with the simplified pre-MIRACLE2 score.
Analyzed feasibility and prognostic precision of the testing methods.
Point-of-care pH testing improved prognostic precision for neurological outcomes.
The simplified pre-MIRACLE2 score was found to be more practical with similar performance.
Integration of these tests into care pathways may enhance patient management but needs further validation.

Abstract

In this study, pre-hospital application of ROSC-MIRACLE2 enables early neurological risk stratification following resuscitated OHCA. Point-of-care pH improves prognostic precision, but is constrained by feasibility, whilst the simplified pre-MIRACLE2 score is more practical with comparable performance. Integration into OHCA care pathways may improve patient stratification and resource utilization but requires further study.

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Cite This Study

Razak et al. (Wed,) studied this question.

synapsesocial.com/papers/69ccb6b416edfba7beb885a5 https://doi.org/https://doi.org/10.1093/ehjacc/zuag036

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