What question did this study set out to answer?

To evaluate the reliability of the Weeke Score for scoring brain MRIs in diagnosing HIE in infants.

April 1, 2026Neuropediatrics0 citations

The Weeke Score is An Easy to Teach and Reliable System for Hypoxic Ischemic Encephalopathy (HIE) Brain MRI Scoring

JLJun LiUniversity of Calgary ZAZarina AssisUniversity of Calgary SVSujith Kumar Reddy Gurram VenkataUniversity of Calgary

Key Points

To evaluate the reliability of the Weeke Score for scoring brain MRIs in diagnosing HIE in infants.
Obtained independent MRI scores from Neuroradiology and Neonatology fellows after training.
Analyzed scores for reliability using intraclass correlation coefficients (ICCs).
Compared scores against a gold standard provided by an experienced Neuroradiologist.
Neonatology fellows showed good reliability with an ICC of 0.87.
Neuroradiology fellows exhibited excellent reliability with an ICC of 0.94.
The Weeke Score demonstrated effective interobserver reliability between novice and experienced readers.

Abstract

MRI is the imaging of choice to diagnose brain injury and prognosticate long term neurodevelopmental outcomes in infants with hypoxic-ischemic encephalopathy (HIE). Independent scoring from Neuroradiology and Neonatology fellows were obtained for 97 brain MRIs for HIE after teaching. Analysis for reliability was compared against a gold standard of an experienced Neuroradiologist. There was good (intraclass correlation coefficient 0.87) reliability for the Neonatology fellow and excellent (intraclass correlation coefficient 0.94) reliability for the Neuroradiology fellow compared to the Neuroradiologist. This suggests that the scoring system used has good interobserver reliability between less experienced readers compared to an experienced reader.

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