A randomized controlled trial of probiotics to reduce the severity of oral mucositis in patients with oropharyngeal carcinoma undergoing concurrent chemoradiotherapy | Synapse
April 1, 2026Journal of Cancer Research and Therapeutics0 citationsOpen Access
A randomized controlled trial of probiotics to reduce the severity of oral mucositis in patients with oropharyngeal carcinoma undergoing concurrent chemoradiotherapy
The aim is to investigate the potential of probiotics to alleviate oral mucositis caused by chemoradiotherapy in patients with oropharyngeal carcinoma.
Conducted a randomized clinical trial
Included patients diagnosed with oropharyngeal carcinoma
Administered probiotics during concurrent chemoradiotherapy
Measured severity of oral mucositis and dysphagia as outcomes
Probiotics significantly reduced the severity of oral mucositis
Patients experienced decreased dysphagia during treatment
Abstract
In this randomized clinical trial of carcinoma oropharynx patients, probiotics reduced the concurrent chemoradiotherapy-induced severe oral mucositis and dysphagia.