In this study, we report a one-pot acyl migration and Nazarov cyclization/fluorination reaction by combining gold and copper catalysis, leading to the rapid construction of α-fluorocyclopentenones without the requirement of intermediate isolation. Moreover, preliminary results have been obtained for the catalytic enantioselective transformation. Notably, this reaction provides an efficient methodology for one-pot synthesis and fluorination reaction.
Cheng et al. (Mon,) studied this question.