Mitochondria play a central role in cell physiology, and in addition to performing their primary function as an energy source, they are involved in processes such as regulating intracellular calcium levels, generating reactive oxygen species, synthesizing many critical compounds, regulating apoptosis, and more. In this regard, maintaining them in a normal state is of great importance, ensuring their transport, intracellular distribution, timely biogenesis, and removal of damaged mitochondria from cells. All of this is defined as cellular mitosis, the maintenance of which involves many cellular structures and, primarily, the cytoskeleton. This review summarizes data on the role of one component of the cytoskeleton, vimentin intermediate filaments, in these processes.
Deeb et al. (Wed,) studied this question.