SCORE2-Diabetes demonstrated superior predictive performance for cardiovascular events compared to the ASCVD risk score in Japanese patients with diabetes mellitus (AUROC 0.688 vs 0.639).
Cohort (n=1,186)
No
Does the SCORE2-Diabetes model improve cardiovascular risk prediction compared to the ASCVD risk score in Japanese patients with diabetes mellitus?
Both ASCVD risk score and SCORE2-Diabetes are valid for predicting cardiovascular events in Japanese patients with diabetes, but SCORE2-Diabetes demonstrates superior predictive performance.
Effect estimate: HR 1.09 (95% CI 1.05-1.14)
p-value: p=<0.001
Diabetes mellitus is a major risk factor for cardiovascular disease (CVD), and prediction models are recommended to identify patients with diabetes mellitus at high CVD risk. However, no risk prediction models have been developed for Japanese patients with diabetes mellitus. Therefore, we aimed to validate the Atherosclerotic Cardiovascular Disease (ASCVD) risk score and Systematic Coronary Risk Evaluation 2-Diabetes (SCORE2-Diabetes) model in Japanese patients with diabetes mellitus.
Singh et al. (Mon,) conducted a cohort in Diabetes Mellitus (n=1,186). SCORE2-Diabetes vs. ASCVD risk score was evaluated on Composite of myocardial infarction and stroke (HR 1.09, 95% CI 1.05-1.14, p=<0.001). SCORE2-Diabetes demonstrated superior predictive performance for cardiovascular events compared to the ASCVD risk score in Japanese patients with diabetes mellitus (AUROC 0.688 vs 0.639).