Aim: The primary objective of this randomized clinical study was to radiologically assess the net bone gain and the reduction of graft volume achieved with the combination of mixed autologous and heterologous bone grafting (BG) alongside hyaluronic acid (HA), providing a comprehensive evaluation of the procedure's efficacy and safety. Materials and Methods: Participants were selected from patients seeking implant treatment at the university hospital between February 2022 and January 2024. The procedure involved sinus elevation using techniques such as physiological water jet pressure (CasKIT), mechanical lifting tips (M.I.S.E.), and the Summers osteotome method. Bone graft biomaterials were introduced after sinus membrane elevation, followed by simultaneous implant placement. Radiological imaging included pre- and postoperative CBCT scans, orthopantomography (OPG), and intraoral periapical radiographs. Results: The study initially involved 16 maxillary sinuses from 8 patients. There was a significant increase in bone height in the Bone Graft (BG) and Hyaluronic acid (HA) groups from the initial measurement (T0) to the first (T1) and second follow-ups (T2). However, there was a significant decrease in bone height between the first and second follow-ups. Conclusion: Both types of grafts are appropriate for maxillary sinus elevation with immediate implant placement. The HA contributed to graft augmentation and stabilization, fostering blood clot formation and preserving its stability.
Dolci Alessandro (Thu,) studied this question.