Phase III Prospective Randomised Study of Netarsudil and Concomitant Latanoprost Efficacy and Safety for Primary Open-Angle Glaucoma or Ocular Hypertension in Japan: J-ROCKET-2

Key Points

• The study aims to assess the efficacy and safety of netarsudil combined with latanoprost for treating primary open-angle glaucoma and ocular hypertension.
• Phase III prospective randomized trial design
• Participants included patients with primary open-angle glaucoma or ocular hypertension
• Intervention involved netarsudil alongside latanoprost
• Efficacy and safety were evaluated using predefined endpoints
• The combination of netarsudil and latanoprost showed improved efficacy compared to standard treatments.
• Safety profiles indicated manageable side effects.
• Trial suggests this combination could be a beneficial option for Japanese patients with glaucoma and ocular hypertension.