Do rapid-acting antihypertensives cause extreme blood pressure reductions exceeding safety limits in patients with hypertensive urgency?
The use of rapid-acting antihypertensives for hypertensive urgency frequently results in unsafe drops in blood pressure, highlighting the need for novel, safer clinical management algorithms.
Our results demonstrate frequent extreme SBP and MAP reductions exceeding safety and autoregulatory limits with rapid-acting antihypertensives and the crucial need to develop and test novel clinical algorithms for the well tolerated and effective management of hypertensive urgency.
Preston et al. (Tue,) studied this question.