This systematic review aimed to consolidate existing literature on Ameloblastoma in Pediatric and Adolescent population with the objective to extract evidence-based data on the diagnosis, treatment and outcomes of Ameloblastoma in individuals under 18 years of age. PRISMA (2020) guidelines were followed and keywords “Ameloblastoma,” “Pediatric,” and “Adolescent” were used in five electronic databases - PubMed, Index Copernicus, LILACS, EBSCO, and Springer.. Ultimately, 47 unique citations were selected for the final review. Details of publication, demographics, clinical presentation, radiography, histopathology, treatment, and follow-up were extracted. The diagnostic mean age was 12.14 years, with slight female predominance (1:1.08). Lesions were commonly seen in the mandible (92%), followed by maxilla (5.33%) and both jaws (2.66%). Radiography revealed a unilocular radiolucency (73.3%), multilocular radiolucency (14.6%) with one peripheral ameloblastoma. Unicystic (77.3%) and Conventional (22.6%) variants were observed histopathologically. Most cases underwent conservative treatment to ensure normal growth but radical resection was undertaken in potentially aggressive lesions. Ameloblastomas represent benign, locally aggressive odontogenic tumours primarily involving the jaws. Distinct clinical, radiographic and histologic patterns have been observed for Pediatric Ameloblastomas, necessitating specialized diagnostic and treatment approaches to accommodate normal growth and development.
Dixit et al. (Thu,) studied this question.