What question did this study set out to answer?

To explore the potential relationship between gastric-type AIS and pyloric-type gastric metaplasia.

April 3, 2026Histopathology0 citationsOpen Access

Endocervical gastric‐type AIS : a rare histologic finding that further supports the hypothesis of a pyloric‐type metaplastic origin

MPMichele Paudice VPVeronica Parrella GSGiulia Scaglione

Key Points

To explore the potential relationship between gastric-type AIS and pyloric-type gastric metaplasia.
Case analysis of gastric-type AIS in endocervical tissue
Histological examination to identify pyloric-type metaplasia
Comparison of histological features in cervical lesions
Identified a case of gastric-type AIS with pyloric-type features
Strengthened the hypothesis of a metaplastic origin
Noted implications for accurate diagnosis in HPV-independent lesions

Abstract

This case supports a possible link between gAIS and pyloric-type gastric metaplasia, underscoring the importance of accurate recognition in HPV-independent cervical lesions.

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