A meta-analysis supporting the role of positive airway pressure therapy in lowering pulmonary artery pressure in obstructive sleep apnoea and obesity hypoventilation syndrome with severe obstructive sleep apnoea

Key Points

• To evaluate the impact of positive airway pressure therapy on pulmonary artery pressure in patients with obstructive sleep apnoea and obesity hypoventilation syndrome.
• Conducted a meta-analysis of studies related to positive airway pressure therapy
• Evaluated the prevalence of pulmonary hypertension in patients with obstructive sleep apnoea and obesity hypoventilation syndrome
• Excluded patients with concurrent cardiovascular and respiratory conditions to isolate effects
• Approximately 30% of obstructive sleep apnoea patients exhibit pulmonary hypertension
• More than 50% of obesity hypoventilation syndrome patients experience pulmonary hypertension
• Positive airway pressure therapy is associated with decreased pulmonary artery pressure